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Blind Signal Separation from Optical Imaging Recordings with Extended Spatial Decorrelation
Citation key Schiessl2000b
Author Schießl, I. and Stetter, M. and Mayhew, J. and McLoughlin, N. and Lund, J. and Obermayer, K.
Pages 573 – 577
Year 2000
ISSN 0018-9294
DOI 10.1109/10.841327
Journal IEEE Transactions on Biomedical Engineering
Volume 47
Number 5
Publisher IEEE
Abstract Optical imaging is the video recording of two-dimensional patterns of changes in light reflectance from cortical tissue evoked by stimulation. We derived a method, extended spatial decorrelation (ESD), that uses second order statistics in space for separating the intrinsic signals into the stimulus related components and the nonspecific variations. The performance of ESD on model data is compared to independent component analysis algorithms using statistics of 4th and higher order. Robustness against sensor noise is scored. When applied to optical images, ESD separates the stimulus specific signal well from biological noise and artifacts.
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